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產品英文名稱 | Human Haptoglobin Protein, His tag |
產品中文名稱 | 重組人觸珠蛋白,His-標簽(Haptoglobin ) |
別名 | Haptoglobin |
表達宿主 | 大腸桿菌 |
種屬 | 人 |
序列 | 氨基酸序列來源于: 人觸珠蛋白(AAA88080.1) (Ile162-Asn406)在n端帶有6×His標簽。 |
蛋白長度 | 重組人觸珠蛋白由245個氨基酸組成,預測分子量為27.2 kDa。 |
純度 | > 95 % ,使用SDS-PAGE檢測 |
特點&優勢 | 通過LAL法測定,每微克蛋白里內毒素含量< 0.1=""> |
產品形式 | 凍干粉,凍干緩沖液為無菌的PBS, pH 7.4. |
基因ID | 3240 |
蛋白序列鏈接 | /uniprotkb/P00738 |
使用中注意事項 | 開蓋使用前,請先離心。本產品為凍干粉,推薦用該產品配套的Reconstitution Buffer進行復溶,且濃度不低于100 µg/mL。客戶可根據后續的實驗需求,進行進一步的稀釋。 |
保存建議 | 凍干蛋白應在 -20°C 下保存 1 年。復溶后,在 2°C 至 8°C 下最多可保存 1 周。 在含有載體蛋白或穩定劑的緩沖液中進一步稀釋(如 0.1%BSA、10%FBS、5%HSA 或 5%trehalose)。BSA、10%FBS、5%HSA 或 5% 海藻糖溶液)中進一步稀釋,蛋白等分應在 -20°C 或 -80°C 下保存 3-6 個月。避免反復凍融循環。 |
運輸條件 | 冰袋運輸(藍冰) |
警告 | 本文列出的產品僅供研究使用,不適用于人類或臨床診斷。我們產品所推薦應用,不建議使用我們的產品去違反任何或許可證。對于使用本產品可能發生的侵權或其他違規行為,我們不承擔任何責任。 |
背景 | Haptoglobin is a glycoprotein, which is synthesized in the liver and circulates in the blood. Haptoglobin is usually produced by liver cells, but it is also produced by other tissues, such as skin, lung and kidney. It is a positive acute phase protein, which binds to free hemoglobin and removes it from circulation to prevent kidney injury and iron loss after hemolysis. Decreased levels can be seen in hemolysis and impaired liver function. A high level is a sign of acute or chronic inflammation. Hemoglobin deficiency or hypohaptoglobinemia is caused by mutation of haptoglobin gene and/or its regulatory region. Haptoglobin is also related to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, susceptibility to primary sclerosing cholangitis, idiopathic Parkinson's disease and the reduction of the incidence of plasmodium falciparum malaria. |
Fig.SDS-PAGE analysis of Human Haptoglobin Protein, His tag