產(chǎn)品名稱：Rabbit Anti-VASP  antibody

Rabbit Anti-VASP  

別名：Vasodilator stimulated phosphoprotein； Vasodilator-stimulated phosphoprotein； VASP； VASP_HUMAN. 

來(lái)源：Rabbit

克隆類型：Polyclonal

濃度：1mg/ml

亞型：IgG

應(yīng)用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反應(yīng)：Human,Mouse,Rat (predicted: Cow,Dog)

理論分子量：40kDa

免疫原：KLH conjugated synthetic peptide derived from human VASP

保存：-20℃
保質(zhì)期：1年

單克隆抗體

產(chǎn)品名稱：Anti-VASP antibody

Mouse Anti-VASP 

別名：Vasodilator stimulated phosphoprotein； Vasodilator-stimulated phosphoprotein； VASP； VASP_HUMAN. 

來(lái)源：Mouse

克隆類型：Monoclonal

濃度：1mg/ml

亞型：IgG

應(yīng)用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反應(yīng): Human

理論分子量：40kDa

免疫原：KLH conjugated synthetic peptide derived from human VASP

保存：-20℃
保質(zhì)期：1年

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

Recombinant human VASP   

Vasodilator stimulated phosphoprotein； Vasodilator-stimulated phosphoprotein； VASP； VASP_HUMAN. 

濃度：1mg/ ml

來(lái)源：Recombinant Human

純度：≥95% SDS-PAGE

表達(dá)系統(tǒng)：Escherichia coli

標(biāo)簽：His tag  

蛋白長(zhǎng)度：Full length protein

內(nèi)毒素水平：<1.000 Eu/µg

純化方法：HPLC

應(yīng)用：SDS-PAGE，Western blot，ELISA

Biological activity,immunology research

保存：-20℃

保質(zhì)期：1年

Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.