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干細胞生長分化因子與人間充質干細胞是屬于研究干細胞科學zui常用的試劑與培養基，目前各大研發機構都從本公司購買，兩者一起購買優惠哦！
小鼠Wnt-3a蛋白（25ug,W3A-M-025 ）基本信息：
Description: Wnt-3a belongs to the Wnt family of signaling proteins that play a key role in maintaining the integrity of embryonic and adult tissues. Expression of Wnt-3a occurs primarily along the dorsal midline across overlapping regions of the Central Nervous System （CNS）. Wnt-3a signaling is essential for various morphogenetic events including embryonic patterning, cell determination, cell proliferation, CNS development, and cytoskeletal formation. like other members of this family, Wnt-3a contains a highly conserved lipid modified cysteine rich domain that is essential for cell signaling. During a biochemical process called the canonical Wnt pathway; Wnt family members bind to and activate seven-pass transmembrane receptors of the Frizzled family ultimay leading to the disruption of β-Catenin degradation. Intracellular accumulation of β-Catenin increases translocation of the protein into the nucleus where it binds to TCF/LEF transcription factors to promote gene expression. Lack of Wnt signaling disrupts transcriptional activation of tumor suppressor genes and has shown to result in neoplastic transformation, oncogenesis, and human degenerative diseases. Recombinant murine Wnt-3a is a monomeric glycoprotein containing 328 amino acid residues. Due to glycosylation, the murine Wnt-3a migrates at an apparent molecular weight of approximay 38.0-41.0 kDa by SDS-PAGE analysis under non-reducing conditions.
Source: cell culture
Molecular Weight: 38-41 kDa Purity: > 75% by SDS-PAGE and HPLC analysis Endotoxin level/內毒素水平: < 0.1 ng per μg of Wnt-3a
Stabilizer: none
Formulation: lyophilized
小鼠Wnt-3a蛋白（25ug,W3A-M-025 ）相關產品：
小鼠wnt-3a蛋白（WNT3A）信號通路（5ug,W3A-M-005）
小鼠wnt-3a蛋白（WNT3A）信號通路（25ug,W3A-M-025）
WNT-3a，小鼠wnt蛋白因子（W3A-M-100）,100ug
WNT-5a，小鼠wnt蛋白因子（W5A-M-005）,5ug
WNT-5a，小鼠wnt蛋白因子（W5A-M-025）,25ug
WNT-5a，小鼠wnt蛋白因子（W5A-M-100）,100ug
小鼠Wnt-3a蛋白（25ug,W3A-M-025 ）應用目的：
小鼠Wnt-3a基因是Wnt基因家族中的重要成員,其編碼表達Wnt-3a信號蛋白.Wnt-3a信號蛋白可以激活經典的Wnt/β-catenin信號通路.Wnt-3a信號蛋白對神經干細胞表現出明顯的促神經元分化的作用.我們應用基因重組的方法,從小鼠胚腦中克隆Wnt-3a cDNA,構建真核表達載體。
小鼠Wnt-3a蛋白（25ug,W3A-M-025 ）英文簡述：
WNT-3a is a member of the WNT family of signaling proteins that play a key role in embryonic development and the integrity of adult tissues. WNT-3a is a prototypic canonical WNT that signals through the beta-catenin pathway. The predicted size of mouse WNT-3a is a monomeric protein containing 333 amino acid residues. Due to glycosylation, it migrates at an apparent molecular weight of 40 kDa by SDS-PAGE analysis under non-reducing conditions.
想更多咨詢小鼠Wnt-3a蛋白（25ug,W3A-M-025 ）,請上海華雅思創生物科技有限公司。上海華雅思創生物科技有限公司是一家專業為生物科學實驗室研究工作者提供生物試劑，細胞培養基，SFM無血清培養基，抗體，細胞因子，實驗器材，實驗耗材等美國進口的高品質產品，優質服務。
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