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產品英文名稱：WNT-3a, Human
產品中文名稱：人重組WNT-3a蛋白
人重組WNT-3a蛋白 產品簡介：
StemRD已研發出一種新穎的表達和純化諸如WNT蛋白等“困難"蛋白的*方法。我們*的處理方法能得到純度和活性均領 于市場方法生產的WNT蛋白。StemRD的WNT蛋白絕不含有現今市場普遍使用的WNT蛋白中含有的某些非特異性成分。
WNT-3a 是WNT 信號蛋白家庭的成員之一，在胚胎成長和成體組織維護方面起關鍵作用。WNT-3a 是典型的通過β-聯蛋白通路發送信號。已有規格的WNT-3a是一個包含328個氨基酸殘基的單鏈蛋白質。由于糖基化，WNT-3a 在非還原條件下用SDS-PAGE處理會明顯損失掉38-41 kDa分子量。StemRD公司生產的WNT-3a是用人體細胞系中Wnt-3a cDNA 在無蛋白培養基上過度表達得到。使用*的純化方法，區別于其它已發表的純化方法，提高蛋白純度。
人重組WNT-3a蛋白 產品特性：
? WNT-3a使用LC/MS 層析，純度大于98%，結構經過NMR驗證
? 生物活性認證：經過生物試驗驗證，優于其它同類型產品
? WNT-3a 是典型的通過β-聯蛋白通路發送信號
? *用于科學研究，非人體使用
WNT-3a, Human 產品英文簡述：
We express and purify WNT proteins by using a proprietary process that is distinctive from the published protocol. Our method results in WNT proteins that are purer and more active than market-leading products which have been associated with non-specific artifacts.
WNT-3a is a member of the WNT family of signaling proteins that play key roles in embryonic development and the maintenance of adult tissues. WNT-3a is a prototypic canonical WNT that signals through the β-catenin pathway. The predicted size of human WNT-3a is a monomeric protein containing 328 amino acid residues. Due to glycosylation, it migrates at an apparent molecular weight of 38 - 41 kDa on SDS-PAGE under non-reducing conditions. StemRD’s WNT-3a is produced from a human cell line overexpressing human Wnt-3a cDNA in protein-free medium. Purification is done by a proprietary process that is distinct from the published method.
WNT all compounds are:
1. >98% pure by LC/MS analysis, and structurally verified by NMR.
2. Bioactivity Certified: tested for biological activities, an advent-age over other supplies.
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