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世聯博研（北京）科技有限公司 |
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—— 銷售熱線 ——
13261877206 |
共聚焦顯微鏡觀察軟骨構建三維力學刺激生物反應器動態周期性壓應力持續循環壓力負荷周期性刺激.
軟骨構建三維力學刺激體外培養多艙生物反應器動態周期性壓應力持續循環壓力負荷周期性刺激誘導軟骨分化組織工程
C9-X CartiGen生物反應器
C9 - X系統被設計成一個多樣品生物反應器系統，能夠支持廣泛的細胞和組織的生長實驗。反應艙zui多可容納9個圓盤形樣品，zui大的直徑8mm大小x 5mm厚。 C9 - X的*的設計集成了內室底部多孔壓板允許通過樣本結構的灌注。此功能可讓研究人員直接通過結構的流動，同時采用壓縮力刺激?？蛇x功能，如額外的機械傳感器和灌注系統定制儀器的具體研究中的應用。
生物反應器可為組織培養物提供不同大小和頻率的壓應變以及不同流量的灌流條件,可控精度高、操作簡單可行、性能穩定
CartiGen Cartilage Bioreactor, The DynaGen Series
Watch a video of the CartiGen （C10-12） bioreactor.
The DynaGen® Series bioreactors provide mechanical stimulation to three dimensional tissue engineered constructs to create physiological conditions in-vitro. The CartiGen system imparts compressive or hydrostatic stress to a cartilage construct. The stress/strain profiles can be defined by the user and can be a simple harmonic （sinusoidal） or a physiological waveform. Applications include the investigation of cell function and differentiation, pharmaceutical benchtop testing, and the seeding and growth of engineered tissues and medical devices. Researchers are currently utilizing these systems in a wide range of research areas including:
C10-1 CartiGen Bioreactor
The C10-1 system has been designed as a single sample bioreactor system that is able to support a wide range of cell and tissue growth experiments utilizing compression. The chamber can accommodate a single sample with a maximum size of 30 mm diameter x 5 mm thick. Optional features such as additional mechanical transducers customize the instrument for the specific research application.
C10-12c CartiGen Bioreactor
The C10-12c system has been designed as a multi-sample bioreactor system that is able to support a wide range of cell and tissue growth experiments. This chamber can accommodate up to 12 disc shaped samples with a maximum size of 10mm diameter x 5mm thick. The C10-12c's unique design includes optical grade windows on the bottom of the chamber, allowing researchers to view their samples with a confocol microscope without interrupting the culturing process. Optional features such as additional mechanical transducers customize the instrument for the specific research application.
C9-x CartiGen Bioreactor
The C9-x system has been designed as a multi-sample bioreactor system that is able to support a wide range of cell and tissue growth experiments. The chamber can accommodate up to 9 disc shaped samples with a maximum size of 8mm diameter x 5mm thick. The C9-x's unique design integrates porous platens within the bottom of the chamber to permit perfusion through the sample constructs. This feature allows researchers to direct flow through the construct while applying oscillatory compressive stimulation. Optional features such as additional mechanical transducers and perfusion systems customize the instrument for the specific research application.
Indexed CartiGen Bioreactor
The Indexed CartiGen （I-Cart） system imparts individualized mechanical compression to 12 cartilage samples. Designed to be placed within a standard incubator, applications include investigating cell function, modulating the growth and development of engineered tissues, or testing drugs and regenerative medicine technologies. For more information on the I-Cart click here.
CartiGen HP Bioreactor
The HP System has been designed as a single or multi-sample bioreactor hydrostatic pressurization system. The chamber can accommodate up to one disc shaped sample up to 50mm diameter x 5mm thick or up to 6 samples that are 30mm diameter X 5mm thick. This system is unlike the other CartiGen Systems in that stress is applied using a high pressure air source. This enables hydrostatic stresses up to 0.5MPa to be applied. For more information on the CartiGen HP click here.
GrowthWorks® Software & Control:
A fifth generation design, the GrowthWorks Software and Control platform includes advanced capabilities, such as multiple waveform control, data acquisition and multi-motor operation. The intuitive software runs on a Windows® laptop computer and features a simple user interface. User defined stimulation profiles are controlled by the software and are readily monitored using graphical displays. Integrated data acquisition routines capture and record data at user prescribed intervals. The GrowthWorks Software is configurable for running four stimulators while simultaneously monitoring up to 16 transducers, allowing the researcher maximum flexibility.
The GrowthWorks Control Hardware features an embedded In CPU, integrated data acquisition and integrated motor drives. Communications between the laptop and control hardware is transmitted over a standard network cable. Primary advantages of the TGT Laptop/Controller approach are reduced physical size and easy upgradability. As future Windows versions or higher performance Laptops become available, either can be replaced without any software or controller changes. This ensures the GrowthWorks control system will be an integral part of your research for many years to come.
GrowthApps Stiffness Measurement & Adaptive Control:
The GrowthApps modules provided added capability to GrowthWorks. The addition of the Stiffness Measurement & Adaptive Control Application enables the system to make real-time measurements of the sample stiffness during culture. Described in U.S. Patent 7,410,792 B2 Instrumented bioreactor with material property measurement capability and process-based adjustment for conditioning tissue engineered medical products., the Application measures the mechanical response of the tissue construct as it is being stimulated and conditioned. The stiffness measurements can be used as guidelines for bench marking progress during culturing or for modifying the stimulation profile. Based upon the measured response, the bioreactor system is then capable of altering the stimulation profile. This technology enables researchers to automatically culture the sample from initial seeding to an implantation-ready state with minimal operator intervention.
三、世聯博研北京科技公司還簽約美國ebersmedical 一個簡單的機械性刺激細胞培養系統，簽約代理以下產品:
四、簽約代理美國B-Bridge細胞牽拉儀（STREX）
美國B-Bridge細胞牽拉儀（STREX）是一種模擬細胞生長過程中的機械應力裝置。通過施加細胞應力，張力腔室中的種子細胞被拉伸或壓縮。施加在細胞上的機械應力更好的模擬了自然動態生理環境。STREX可控制施加在細胞上的應力級別，部分型號可與顯微鏡聯用。
ST-140-04
ST-140-10
| CARTILAGE | |||||
| Key: S=Standard, A=Available, - = not available | |||||
| CHAMBERS | C1 | C10-12c | C9-x | ||
| Individual sample growth chamber | S | S | S | ||
| Multi-sample growth chamber | - | S | S | ||
| Perfusion and instrumentation ports per chamber | - | - | 9 | ||
| Max construct size: 30 mm diameter by 5 mm thick | S | - | - | ||
| Max construct size: 10 mm diameter by 5 mm thick | S | S | - | ||
| Max construct size: 6 mm diameter by 5 mm thick | S | S | S | ||
| Sample visualization via confocal microscopy | - | S | - | ||
| STIMULATION | |||||
| Axial stimulator and reaction frame | S | S | S | ||
| Compressed air and manifold | - | - | - | ||
| CONTROLS | |||||
| Controller software, computer, and monitor | S | S | S | ||
| Power supplies and cabling | S | S | S | ||
| Mean flow control | A | - | S | ||
| Dynamic flow control | A | - | S | ||
| TISSUE MONITORING | |||||
| Non-contact flow sensors | A | A | A | ||
| Axial load cell | S | S | S | ||
| Pressure transducer | - | - | - | ||
| ACCESSORIES | |||||
| Media reservoir | S | - | S | ||
| Incubator | A | A | A | ||
| BENEFITS | |||||
| All-autoclavable components | S | S | S | ||
| Medium change without opening chamber via luer fittings | - | - | S | ||
| Increased sterility with fast and clean sample change and access | S | S | S | ||
| Lightweight design for easy handling | S | S | S | ||
| Easily cleaned surface finishes | S | S | S | ||
| Compact design for fit in standard incubators 6.5cubic ft | S | S | S | ||
| * satisfaction guaranteed warranty | S | S | S | ||
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