 |
北京西美杰科技有限公司
主營產品： 生物學檢測試劑盒,化學試劑,蛋白質氧化損傷,抗原抗體 |
聯系電話
18210960361
公司信息
- 聯系人：
- 西美杰
- 電話：
- 400-050-4006
- 手機：
- 18210960361
- 售后電話：
- 010-88597838
- 地址：
- 北京市海淀區金源時代商務中心B座10F
- 郵編：
- 100097
- 網址：
- www.xmjsci.com
jena bioscience抗病毒核苷/核苷酸類似物
2020-3-4 閱讀(1027)
西美杰代理jena bioscience抗病毒核苷/核苷酸類似物--助力新型冠狀病毒相關藥物研發
持續近兩個多月的新型冠狀病毒感染的肺炎疫情牽動著每一個人的心，為了打贏這場疫情防控狙戰，搞清致病機理，研發抗病毒相關藥物和疫苗刻不容緩。Jena bioscience品牌有豐富的抗病毒核苷酸/核苷酸類似物，助力抗病毒的藥物研發。
抗病毒核苷及核苷酸類似物主要有:
抗病毒核苷/核苷酸類似物可以通過抑制病毒復制的幾個關鍵過程來抑制病毒繁殖，它們通過與天然的dNTP/NTP競爭結合到新的病毒核酸中，從而導致鏈終止或者誘變。在細胞培養實驗中，可以用抗病毒核苷酸的非磷酸化核苷變體，這種核苷酸在細胞內被多種病毒和/或宿主激酶激活，從而發揮(tri)磷酸化形式的抗病毒作用。
西美杰代理jena bioscience抗病毒核苷/核苷酸類似物--助力新型冠狀病毒相關藥物研發
熱銷抗病毒核苷/核苷酸類似物：
貨號 | 品名 | 規格 |
NU-1605S | 3TCMP | 10 μl (10 mM) |
NU-1605L | 3TCMP | 5 x 10 μl (10 mM) |
NU-1606S | 3TCTP | 5 μl (10 mM) |
NU-1606L | 3TCTP | 5 x 5 μl (10 mM) |
NU-1603S | d4TMP | 20 μl (10 mM) |
NU-1603L | d4TMP | 5 x 20 μl (10 mM) |
NU-1601S | AzTMP | 20 μl (10 mM) |
NU-1601L | AzTMP | 5 x 20 μl (10 mM) |
NU-989S | AzTTP | 10 μl (100 mM) |
NU-989L | AzTTP | 5 x 10 μl (100 mM) |
NU-875 | ara-Adenosine-5'-monophosphate (ara-AMP) | 2 mg |
NU-1111S | 50 μl (10 mM) | |
NU-1111L | ara-Adenosine-5'-triphosphate (ara-ATP) | 5 x 50 μl (10 mM) |
NU-876 | Acyclovir-5'-monophosphate | 2 mg |
NU-877 | Acyclovir-5'-triphosphate | 2 mg |
NU-021-2 | Ribavirin-5'-monophosphate | 2 mg |
NU-1105S | 20 μl (10 mM) | |
NU-1105L | Ribavirin-triphosphate | 5 x 20 μl (10 mM) |
N-DN-8234-100 | β-L-2'-Deoxythymidine | 100 mg |
NU-896S | 10 μl (100 mM) | |
NU-896L | 6-Aza-UTP | 5 x 10 μl (100 mM) |
NU-974 | Tenofovir | 100 mg |
NU-975 | Tenofovir-diphosphate | 1 mg |
NU-989S | 10 μl (100 mM) | |
NU-989L | AzTTP | 5 x 10 μl (100 mM) |
NU-275S | 10 μl | |
NU-275L | Ganciclovir-triphosphate | 5 x 10 μl |
西美杰是Jena bioscience中國總代理\德國耶拿總代理，為用戶提供完善的技術與售后服務。西美杰會更好的協助科研工作者的實驗工作，支持全國戰“疫”，早日戰勝病毒。武漢加油！中國加油！
參考文獻：
1] Huang at al. (2011) Effect of reverse transcriptase inhibitors on Line-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition. BMC Biochemistry 12:18.
[2] Vaccaro at al. (1999) Mechanism of Inhibition of the Human Immunodeficiency Virus Type 1 Reverse Transcriptase by d4TTP: an Equivalent Incorporation Efficiency Relative to the Natural Substrate dTTP. Antimicrob. Agents Chemother. 44 (1):217.
[3] Jaju at al. (1995) Human immunodeficiency virus type 1 reverse transcriptase. 3'-Azidodeoxythymidine 5'-triphosphate inhibition indicates two-step binding for template-primer. J. Biol. Chem. 270 (17):9740.
[4] Furmann at al. (1979) Inhibition of Herpes Simplex Virus-Induced DNA Polymerase Activity and Viral DNA Replication by 9-(2-Hydroxyethoxymethyl)guanine and Its Triphosphate. J. Virol. 29 (2):154.
[5] Muller at al. (1977) Inhibition of Herpesvirus DNA synthesis by 9-O-D-Arabinofuranosyladenine in cellular and cell-free systems. Ann. N.Y. Acad. Sci. 284:34.
[6] Crotty at al. (2000) The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen. Nature Medicine 6 (12):1375.
[7] Ray at al. (2009) Metabolism of antiviral nucleosides and nucleotides. In: Antiviral Research: Strategies in antiviral drug discovery (LaFemina). ASM Press.
[8] Simons at al. (2005) Recent Advances in Antiviral Nucleoside and Nucleotide Therapeutics. Current Topics in Medicinal Chemistry 5:1191.
北京西美杰科技是AppliChem代理，Phytotech代理，seracare KPL代理，博百歐代理，Alzet代理，Lifespan代理，Agrisera代理，Jena Bioscience代理，Cell Biolabs代理，Mybiosource代理，Mirus代理，PCT代理，Advanced Biomatrix代理，Cygnus代理，Pfanstiehl代理，Kerry代理
